Endocrine Abstracts

Introduction: Serum 25(OH) vitamin D levels are shown to be significantly lower and associated with lower remission rates in Graves disease. In this study we aimed to investigate the impact of baseline vitamin D levels on thyroid volume in patients with new-onset Graves disease.Materials and methods: This is a monocenter cross sectional study with a total of 61 new-onset Graves disease patients (n:61, F: 40, M:21) who were divided into two groups accordi...

During the past decades, incidence of adrenal tuberculosis has been greatly decreased due to the introduction of antituberculosis drugs. It is reported that primary adrenal insufficiency (PAI) results from adrenal tuberculosis accounting for only 15%–20% patients in developed countries. Adrenal tuberculosis is the major cause of chronic PAI especially in developing countries. A 53 year old man presented with a 3 month history of generalized weakness, anorexia, weight loss...

Aim: It is well known that there is a strong relationship between chronic inflammation and tumorigenic process. The cytological diagnosis of follicular neoplasm (FN) carries a 20–30% risk of malignancy for thyroid nodules. In this study, we aimed to evaluate whether preoperative neutrophil to lymphocyte ratio (NLR) is a predictive factor for malignancy in thyroid nodules diagnosed as FN on cytology.Materials and methods: A total of 139 patients with...

Addison’s disease (AD), is an autoimmune disorder. However, its association with connective tissue diseases is rare. Here, we report a case of AD associated with ankylosing spondylitis (AS).Case: A 57-year-old male patient admitted to internal medicine polyclinic with complaints of debility and anorexia. In the physical examination, he has hyperpigmentation on his skin, gingiva and palm lines. Blood pressure was 80/50 mmHg, pulse was 64/min. The oth...

Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. A disintegrin and metalloproteinase with thrombospondin-like motifs (ADAMTS) are involved in inflammation and fertility. The aim of this investigation was to evaluate to serum levels of ADAMTS1, ADAMTS5, ADAMTS9, IL17, IL23, IL33 and to find out the relationship between these inflammatory cytokines and ADAMTSs in PCOS patients.Met...